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1.
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Classification of unknown primary tumors with a data-driven method based on a large microarray reference database
Kalle
A
Ojala,
Sami
K
Kilpinen,
Olli
P
Kallioniemi
Genome Medicine 2011, 3:63 (17 October 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
wAGEP is a scalable, adaptable method that can be used to accurately classify cancers of unknown primary origin by aligning microarray profiles against a microarray reference database.
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2.
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A systems-biology approach to understanding the ciliopathy disorders
Ji Eun
Lee ,
Joseph
G
Gleeson
Genome Medicine 2011, 3:59 (26 September 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Lee and Gleeson provide an overview of the varied diseases caused by defects in ciliary function, the ciliopathies, and the ways in which high-throughput approaches could lead to treatments.
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3.
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Systems medicine and the public's health
Wylie
Burke,
Susan
Trinidad
Genome Medicine 2011, 3:47 (27 July 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Burke and Trinidad discuss the systems medicine and integrated care approach proposed by Bousquet et al. as a strategy to combat non-communicable diseases and promote public health.
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4.
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Systems medicine and integrated care to combat chronic noncommunicable diseases
Jean
Bousquet,
Josep
M
Anto,
Peter
J
Sterk,
Ian
M
Adcock,
Kian
Chung,
Josep
Roca,
Alvar
Agusti,
Chris
Brightling,
Anne
Cambon-Thomsen,
Alfredo
Cesario,
Sonia
Abdelhak,
Stylianos
E
Antonarakis,
Antoine
Avignon,
Andrea
Ballabio,
Eugenio
Baraldi,
Alexander
Baranov,
Thomas
Bieber,
Joël
Bockaert,
Samir
Brahmachari,
Christian
Brambilla,
Jacques
Bringer,
Michel
Dauzat,
Ingemar
Ernberg,
Leonardo
Fabbri,
Philippe
Froguel,
David
Galas,
Takashi
Gojobori,
Peter
Hunter,
Christian
Jorgensen,
Francine
Kauffmann
et al.
Genome Medicine 2011, 3:43 (6 July 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A holistic and patient-centered strategy for tackling non-communicable diseases is proposed, based on the principles of predictive, preventive, personalized and participatory (P4) medicine.
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5.
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Methods for the de-identification of electronic health records for genomic research
Khaled
El Emam
Genome Medicine 2011, 3:25 (27 April 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
As electronic health records are increasingly used in research, Khaled El Emam reviews the need for effective de-identification methods to reduce the risk of re-identification for disclosed data.
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6.
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Genome Medicine: past, present and future
Charles
Auffray,
Timothy
Caulfield,
Muin
J
Khoury,
James
R
Lupski,
Matthias
Schwab,
Timothy
Veenstra
Genome Medicine 2011, 3:6 (31 January 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
As Genome Medicine reaches its second anniversary, our Section Editors identify the most exciting recent breakthroughs and offer their opinions on what the future of genomic medicine might hold.
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7.
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The in silico macrophage: toward a better understanding of inflammatory disease
Peter
Ghazal,
Steven
Watterson,
Kevin
Robertson,
David
C
Kluth
Genome Medicine 2011, 3:4 (22 January 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
In silico modeling of the human macrophage could lead to a better understanding of immune inflammatory response and potentially help to develop therapies for autoimmune diseases
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