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#personalizedmedicine

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	1.	Meeting report Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing Mia Wadelius, Ana Alfirevic Genome Medicine 2011, 3:78 (28 December 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mia Wadelius and Ana Alfirevic present highlights from the Cold Spring Harbor and the Wellcome Trust 2011 meeting on 'Pharmacogenomics and Personalized Medicine'.
	2.	Review Pharmacogenetics in type 2 diabetes: potential implications for clinical practice Chunmei Huang, Jose C Florez Genome Medicine 2011, 3:76 (29 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chunmei Huang and Jose Florez review recent insights into type 2 diabetes that are emerging from pharmacogenetic and pharmacogenomic studies, and discuss the potential for clinical translation.
	3.	Research highlight Predicting the pathogenesis of influenza from genomic response: a step toward early diagnosis Eric Bortz, Adolfo García-Sastre Genome Medicine 2011, 3:67 (24 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Bortz and Garcia-Sastre highlight recent insights into the molecular events underlying host response to influenza virus that could allow early prediction of symptomatic or asymptomatic infection.
	4.	Research Pharmacogenetic testing affects choice of therapy among women considering tamoxifen treatment Wendy Lorizio, Hope Rugo, Mary S Beattie, Simone Tchu, Teri Melese, Michelle Melisko, Alan HB Wu, H Jeffrey Lawrence, Michele Nikoloff, Elad Ziv Genome Medicine 2011, 3:64 (4 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The choice of medication for breast cancer patients was changed after CYP2D6 genotyping, demonstrating for the first time that pharmacogenetics can shape clinical treatment decisions.
	5.	Research Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort Katherine R Smith, Vijayaprakash Suppiah, Kate O'Connor, Thomas Berg, Martin Weltman, Maria Abate, Ulrich Spengler, Margaret Bassendine, Gail Matthews, William L Irving, Elizabeth Powell, Stephen Riordan, Golo Ahlenstiel, Graeme J Stewart, Melanie Bahlo, Jacob George, David R Booth, Genome Medicine 2011, 3:57 (31 August 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Novel variants in the IL28B gene region, which predict lack of response to conventional treatment of hepatitis C virus, are identified through massively parallel sequencing using pooled DNA.
	6.	Review Genetics and genomics of radiotherapy toxicity: towards prediction Catharine M West, Gillian C Barnett Genome Medicine 2011, 3:52 (23 August 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Catharine West and Gillian Barnett review the latest advances in radiotherapy and the recent genome-wide studies that have identified genetic variants linked to radiotoxicity.
	7.	Review Biomarkers in solid organ transplantation: establishing personalized transplantation medicine Silke Roedder, Matthew Vitalone, Purvesh Khatri, Minnie M Sarwal Genome Medicine 2011, 3:37 (8 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Minnie Sarwal and colleagues review the rocky road to regulatory approval in the search for biomarkers for organ transplants that will help predict the chances of success and increase graft survival.
	8.	Research highlight Personalizing carbamazepine therapy Taisei Mushiroda, Yusuke Nakamura Genome Medicine 2011, 3:28 (30 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mushiroda and Nakamura highlight recent studies that could facilitate the development of genetic tests to predict individuals at risk for serious adverse reactions to carbamazepine.
	9.	Review Predicting treatment outcome in classical Hodgkin lymphoma: genomic advances Enrico Derenzini, Anas Younes Genome Medicine 2011, 3:26 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Derenzini and Younes review advances in genomic technologies that have allowed the identification of new biomarkers for predicting disease and treatment outcome in classical Hodgkin lymphoma.
	10.	Meeting report The challenges and hopes of personalized cancer medicine Wa Xian, Frank McKeon Genome Medicine 2011, 3:22 (19 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the Genome Institute of Singapore and the Fritz Bender Stiftung joint meeting on 'Personalized Cancer Medicine: Towards Individualized Cancer Treatments', Singapore, 21-23 February 2011.
	11.	Meeting report Stem cells in drug discovery, regenerative medicine and cancer C Bart Rountree Genome Medicine 2011, 3:15 (14 March 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the Stem Cells World Congress held in San Diego, USA, 24-25 January 2011
	12.	Review Prospects for personalizing antiviral therapy for hepatitis C virus with pharmacogenetics John E Tavis, Maureen J Donlin, Rajeev Aurora, Xiaofeng Fan, Adrian M Di Bisceglie Genome Medicine 2011, 3:8 (8 February 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Antiviral therapy for hepatitis C will change dramatically in the near future as our understanding of how host and viral genetic variation affect the treatment outcome improves.
	13.	Editorial Genome Medicine: past, present and future Charles Auffray, Timothy Caulfield, Muin J Khoury, James R Lupski, Matthias Schwab, Timothy Veenstra Genome Medicine 2011, 3:6 (31 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary As Genome Medicine reaches its second anniversary, our Section Editors identify the most exciting recent breakthroughs and offer their opinions on what the future of genomic medicine might hold.
	14.	Review Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies Emmie de Wit, Heinz Feldmann, Vincent J Munster Genome Medicine 2011, 3:5 (27 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary There is currently no effective treatment for human Ebolavirus infection, but research into vaccines and antiviral and antisense therapies in non-human primates is showing promise.
	15.	Meeting report Pharmacogenetics and pharmacogenomics: practical applications in routine medical practice Anke-Hilse Maitland-van der Zee, Ana Alfirevic Genome Medicine 2010, 2:69 (21 September 2010) Abstract \| Full text \| PDF \| PubMed
	16.	Review Pharmacogenomic considerations in the opioid management of pain Paul J Jannetto, Nancy C Bratanow Genome Medicine 2010, 2:66 (15 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Pharmacogenomics can lead to more efficient opioid selection to minimize adverse drug reactions and improve patient outcome.
	17.	Review Pharmacogenomic insights into treatment and management of statin-induced myopathy Bas JM Peters, Olaf H Klungel, Frank L Visseren, Anthonius de Boer, Anke-Hilse Maitland-van der Zee Genome Medicine 2009, 1:120 (29 December 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Genotyping in patients suffering from statin-induced myopathy may help to personalize the choice of statin by reducing the chance of developing this rare but serious side-effect.