Genome science and health disparities: a growing success story?
Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MA 20892-5635, USA
Genome Medicine 2013, 5:61 doi:10.1186/gm465Published: 29 July 2013
First paragraph (this article has no abstract)
Ten years after the completion of the Human Genome Project, researchers are using DNA to shed light on human history and health. A significant finding of the Human Genome Project and subsequent spin-off projects is that human populations are considerably more similar than different at the DNA level, yet it is now well recognized that genetic differences between ancestral and ethnic groups can have important evolutionary and medical relevance. Here, we reflect on how scientists are taking advantage of these observations to provide insight into complex social and medical issues, such as health disparities and variable drug response.