Review

Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability

Xuemei Fu and Yang Xu

Genome Medicine 2012, 4:55 (28 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Yang Xu and Xuemei Fu review recent challenges for the clinical application of ESCs and iPSCs, including epigenetic and genetic abnormalities, a risk of teratomas, and immunogenicity.

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