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Musings

Public perception of stem cell and genomics research

M William Lensch

Author Affiliations

Department of Pediatrics, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA

Harvard Stem Cell Institute, Holyoke Center, 1350 Massachusetts Avenue, Cambridge, MA 02138, USA

Division of Hematology/Oncology, Children's Hospital Boston, 1 Blackfan Circle, Boston, MA 02115, USA

Genome Medicine 2011, 3:44  doi:10.1186/gm260

Published: 6 July 2011

First paragraph (this article has no abstract)

The confluence of human stem cell and genome research is laden with opportunity. Information gleaned from the Human Genome Project (HGP) has already done much to expand our understanding of human biology and disease (reviewed in [1]). The same can be said of human pluripotent stem cell (hPSC) research involving human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs). For translational stem cell research, especially where it involves reprogramming of mature cells to make iPSCs and their subsequent directed differentiation to other clinically useful cells and tissues, obtaining a deeper understanding of the role of genome-wide transcriptional and epigenetic alterations will be invaluable. Taking the stem cells and genomics relationship to the next level seems like a good idea.