Figure 3.

Hematopoiesis in zebrafish and humans, and known zebrafish blood mutants. The stages of hematopoiesis are illustrated, with the genes and mutants identified as affecting each stage shown (red, zebrafish blood mutants; blue, genes altered by the mutations) and the processes in bold below. Bottom: the sites and times of the events shown in human and zebrafish. AGM, aorta gonad mesonephros; CHT, caudal hematopoietic tissue; dpf, days post-fertilization; hpf, hours post-fertilization; HSC, hematopoietic stem cell.