Genome Medicine | Volume 3 Issue 11

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	Volume 3 Issue 11
	Comment
	Research highlight RNA-Seq and find: entering the RNA deep field Adam Roberts, Lior Pachter Genome Medicine 2011, 3:74 (22 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Lior Pachter and Adam Roberts discuss the advantages of a new method, RNA CaptureSeq, for the detection of low-abundance transcripts potentially important for disease, within the RNA "deep field".
	Research highlight Circulating microRNAs as biomarkers - True Blood? Nathalie Schöler, Christian Langer, Florian Kuchenbauer Genome Medicine 2011, 3:72 (23 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Florian Kuchenbauer and colleagues highlight a recent study revealing that blood-borne microRNA expression data or the "miRNome" could be a powerful tool for the blood-based diagnosis of disease.
	Review
	Review Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine Jonghwan Kim, Stuart H Orkin Genome Medicine 2011, 3:75 (29 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Jonghwan Kim and Stuart Orkin review recent genome-scale and systems approaches to understand the regulatory networks that are common to embryonic stem (ES) cells and cancer.
	Review Pharmacogenetics in type 2 diabetes: potential implications for clinical practice Chunmei Huang, Jose C Florez Genome Medicine 2011, 3:76 (29 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chunmei Huang and Jose Florez review recent insights into type 2 diabetes that are emerging from pharmacogenetic and pharmacogenomic studies, and discuss the potential for clinical translation.
	Report
	Meeting report Epigenomic insights into common disease Kate Revill, Benjamin Tycko Genome Medicine 2011, 3:71 (15 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Revill and Tycko report on the Wellcome Trust Scientific Conference on 'Epigenomics of Common Diseases', highlighting this fast-moving field with particular emphasis on genome-wide studies.
	Meeting report Using DNA sequencers as stethoscopes Melissa Gymrek, Yaniv Erlich Genome Medicine 2011, 3:73 (21 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gymrek and Erlich discuss the success stories and challenges of translating genomic research into the clinic highlighted at the Cold Spring Harbor Laboratory meeting on 'Personal Genomes'.
	Research
	Research Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression Rotem Ben-Hamo, Sol Efroni Genome Medicine 2011, 3:77 (28 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Network-based analysis of gene expression data reveals a role for the p38 network and affiliated hsa-miR-9 in glioblastoma multiforme progression, implicating new biomarkers for predicting survival.