Genome Medicine | Volume 2 Issue 8

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	Volume 2 Issue 8
	Comment
	Commentary Shared pathways to infectious disease susceptibility? Chiea C Khor, Martin L Hibberd Genome Med 2010, 2:52 (10 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Genomic research so far suggests that host susceptibility to different pathogens is controlled by discrete genes and pathways, but as technology develops it may unravel shared mechanisms across multiple pathogen groups.
	Editorial Predictive, preventive, personalized and participatory medicine: back to the future Charles Auffray, Dominique Charron, Leroy Hood Genome Medicine 2010, 2:57 (26 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The pioneering work of Jean Dausset on the human leukocyte antigen system provides lessons that should be applied to systems medicine.
	Review
	Minireview Environmental exposures and mutational patterns of cancer genomes Gerd P Pfeifer Genome Med 2010, 2:54 (16 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Whole-genome sequences of cancers reveal the different kinds of mutation caused by environmental carcinogens.
	Minireview Recent insights into the role of NF-kappaB in ovarian carcinogenesis Ayesha B Alvero Genome Medicine 2010, 2:56 (25 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary NF-κB plays a role in the initiation and progression of ovarian cancer and represents a potential target for the development of novel therapeutics for this type of cancer.
	Review Prenatal diagnosis of fetal aneuploidies: post-genomic developments Sinuhe Hahn, Laird G Jackson, Bernhard G Zimmermann Genome Medicine 2010, 2:50 (5 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Non-invasive prenatal diagnosis of fetal aneuploidies may soon become possible with new genomic and proteomic technologies.
	Review Genomic imprinting in diabetes Braxton D Mitchell, Toni I Pollin Genome Med 2010, 2:55 (23 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Genetic imprinting is known to have a role in 6q24-related transient neonatal diabetes, and recent research has also revealed parent of origin effects in type I and II diabetes mellitus.
	Correspondence
	Correspondence Translational bioinformatics in the cloud: an affordable alternative Joel T Dudley, Yannick Pouliot, Rong Chen, Alexander A Morgan, Atul J Butte Genome Medicine 2010, 2:51 (6 August 2010) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Cloud-based analysis offers a valid alternative both in terms of performance and cost to local computational clusters for the integration and analysis of large-scale genomic datasets relevant for translational research.
	Correspondence Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets Charles Swanton, James M Larkin, Marco Gerlinger, Aron C Eklund, Michael Howell, Gordon Stamp, Julian Downward, Martin Gore, P Andrew Futreal, Bernard Escudier, Fabrice Andre, Laurence Albiges, Benoit Beuselinck, Stephane Oudard, Jens Hoffmann, Balázs Gyorffy, Chris J Torrance, Karen A Boehme, Hansjuergen Volkmer, Luisella Toschi, Barbara Nicke, Marlene Beck, Zoltan Szallasi Genome Med 2010, 2:53 (11 August 2010) Abstract \| Full text \| PDF \| PubMed