Genome Medicine | Volume 2 Issue 6

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	Volume 2 Issue 6
	Comment
	Musings So what have data standards ever done for us? The view from metabolomics Julian L Griffin, Christoph Steinbeck Genome Med 2010, 2:38 (24 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Metabolomic data standardization is lagging behind some other research fields, but there would be great benefits if all metabolomic data were submitted to a central repository in a standard format.
	Review
	Minireview ABO blood group and other genetic variants associated with pancreatic cancer Anne Lennon, Alison P Klein, Michael Goggins Genome Medicine 2010, 2:39 (22 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Recent genome-wide association studies of pancreatic cancer have resurrected hypotheses of associations with ABO blood group.
	Minireview Serotonin transporter polymorphisms and panic disorder Johannes Schumacher, Jürgen Deckert Genome Med 2010, 2:40 (29 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The identification of polymorphisms of the serotonin transporter gene SLC6A4 as risk variants for panic disorder could pave the way for a better understanding of the pathophysiology of anxiety disorders and the development of prevention strategies.
	Review Genomic insights into early-onset obesity Hélène Choquet, David Meyre Genome Medicine 2010, 2:36 (23 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Genomic research is improving our understanding of the genetic factors that play a role in the development of early-onset obesity and may pave the way for personalized preventive strategies and therapy.
	Review Clinical proteomics of myeloid leukemia Sigrun M Hjelle, Rakel B Forthun, Ingvild Haaland, Håkon Reikvam, Gry Sjøholt, Øystein Bruserud, Bjørn T Gjertsen Genome Med 2010, 2:41 (29 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Research into the leukemic cell proteomes should lead to the development of molecular diagnostic tools and the identification of novel biomarkers for the prediction of response to therapy in myeloid leukemias, opening new avenues for personalized medicine.
	Research
	Research High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-κB-complex-dependent gene expression in human heart failure Mun-Kit Choy, Mehregan Movassagh, Lee Siggens, Ana Vujic, Martin Goddard, Ana Sánchez, Neil Perkins, Nichola Figg, Martin Bennett, Jason Carroll, Roger Foo Genome Medicine 2010, 2:37 (14 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A cooperative transcription factor complex involving p53, NF-kappa-B and STAT3 is responsible for the transcriptional regulation of miRNA-21, a microRNA relevant for the pathology of heart failure.