Table 4

Comparison of miRNA and mRNA expression levels for discordant twins and sib pairs for miR-219 and its target, PLK2, and for miR-29b and its target, ID3

miRNA (target)

A361/C360

A809/C810

A809/C813

A2369/C2368

A2369/C2357

A366/C365

A2769/C2772

Average


miR-219

(PLK2)

-1.447

(0.414)

-1.089

(0.147)

-2.330

(NA)

-2.390

(NA)

-0.175

(NA)

0.398

(0.314)

-1.176

(0.456)

-1.173

(0.333)

miR-29b

(ID3)

0.585

(-0.406)

1.720

(-0.187)

1.287

(-0.574)

0.395

(-0.603)

1.315

(0.070)

2.939

(-0.152)

0.061

(-0.233)

1.186

(-0.298)


The first three columns are log2 ratios for discordant monozygotic twins, while the last four columns are ratios for sib-pair comparisons. NA, no expression ratio obtained for this gene because an intensity value for either the autistic or control sample was missing.

Sarachana et al. Genome Medicine 2010 2:23   doi:10.1186/gm144

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