Table 1

Significantly differentially expressed human miRNAs

Clone ID

miRNA

log2 ratio

P-value


Down-regulated

SM10801

hsa-miR-182-AS

-1.54

1.44E-03

hSQ018350

hsa-miR-136

-1.50

2.28E-03

SM10637

hsa-miR-518a

-1.45

3.52E-03

hSQ045460

hsa-miR-153-1

-1.41

5.07E-03

SM11115

hsa-miR-520b

-1.38

6.71E-03

SM10529

hsa-miR-455

-1.30

1.25E-02

hHM044864

hsa-miR-326

-1.24

1.95E-02

SM10553

hsa-miR-199b

-1.23

1.96E-02

miR211

hsa-miR-211

-1.23

2.04E-02

hSQ016068

hsa-miR-132

-1.22

2.20E-02

SM10792

hsa-miR-495

-1.20

2.43E-02

hSQ025962

hsa-miR-16-2

-1.19

2.54E-02

hHM044822

hsa-miR-190

-1.18

2.69E-02

hHM044960

hsa-miR-219

-1.17

2.98E-02

hHM045056

hsa-miR-148b

-1.16

3.01E-02

hHM044897

hsa-miR-189

-1.16

3.06E-02

hHM045063

hsa-miR-133b

-1.13

3.59E-02

hSQ018899

hsa-miR-106b

-1.11

4.11E-02

hHM044849

hsa-miR-367

-1.10

4.21E-02

SM10740

hsa-miR-139

-1.10

4.32E-02

Up-regulated

hHM044819

hsa-miR-185

1.44

4.04E-03

hHM044919

hsa-miR-103

1.31

1.20E-02

hHM044733

hsa-miR-107

1.26

1.68E-02

hHM044918

hsa-miR-29b

1.24

1.88E-02

hHM045013

hsa-miR-194

1.22

2.11E-02

SM10729

hsa-miR-524

1.22

2.21E-02

hHM044804

hsa-miR-191

1.21

2.23E-02

SM11334

hsa-miR-376a-AS

1.19

2.53E-02

SM10789

hsa-miR-451

1.19

2.64E-02

hHM044971

hsa-miR-23b

1.17

2.95E-02

miR195

hsa-miR-195

1.16

3.02E-02

SM10711

hsa-miR-23b

1.16

3.03E-02

SM10310

hsa-miR-342

1.15

3.24E-02

SM10644

hsa-miR-23a

1.14

3.36E-02

hSQ001775

hsa-miR-186

1.14

3.43E-02

miR25

hsa-miR-25

1.14

3.55E-02

SM10575

hsa-miR-519c

1.13

3.71E-02

SM10238

hsa-miR-346

1.12

3.80E-02

hHM044950

hsa-miR-205

1.12

3.80E-02

hHM044743

hsa-miR-30c

1.11

3.98E-02

hSQ027766

hsa-miR-93

1.10

4.18E-02

hHM045009

hsa-miR-186

1.08

4.67E-02

hHM044831

hsa-miR-106b

1.08

4.86E-02


Forty-three significantly differentially expressed human miRNAs were identified by Pavlidis Template Matching (PTM) analysis (P < 0.05). The log2 ratios for all miRNAs were calculated from the average of the log2 ratio across all autistic samples over the average of the log2 ratio across all control samples.

Sarachana et al. Genome Medicine 2010 2:23   doi:10.1186/gm144

Open Data