Table 1

Characteristics of the 3 subject populations in the study

T2D (n = 45)

IGT (n = 26)

NGT (n = 47)

Age

54.8 ± 10.2

56.4 ± 10.7

51.3 ± 10.7

BMI

31.4 ± 6.2

30.9 ± 6.1

31.1 ± 7.2

VO_2max

26.9 ± 8.4

28.2 ± 9.7

29.5 ± 10.5

Fasting glucose

9.8 ± 4.4*

5.9 ± 0.5^†

5.0 ± 0.4

Fasting insulin

91.2 ± 8.9^†

88.2 ± 13.5^‡

56.6 ± 8.3

HOMA1_log

0.67 ± 0.07*

0.46 ± 0.05*

0.20 ± 0.05

2-h glucose (OGTT)

17.9 ± 5.5*

7.4 ± 2.4^†

5.5 ± 1.2

HbA1c

7.4 ± 1.8*

5.8 ± 0.3^†

5.5 ± 0.2

Data are mean ± standard deviation. BMI, body mass index; VO_2max, ml/kg/minute; Fasting glucose and 2-h glucose tolerance is mmol/L; HbA1c is percentage glycosylated hemoglobin. *P < 0.001 when compared with either NGT or IGT; ^†P < 0.01 when compared with the NGT group; ^‡P = 0.07 when compared with the NGT group. OGTT, oral glucose tolerance test.

Gallagher et al. Genome Medicine 2010 2:9   doi:10.1186/gm130