Genome Medicine


Open Access Highly Access Research

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

Iain J Gallagher1, Camilla Scheele3,2, Pernille Keller1,2, Anders R Nielsen2, Judit Remenyi4, Christian P Fischer2, Karim Roder1, John Babraj1, Claes Wahlestedt5, Gyorgy Hutvagner4, Bente K Pedersen2 and James A Timmons3,1,7,6*

Author Affiliations

1 Translational Biomedicine, Heriot-Watt University, Edinburgh, EH14 4AS, UK

2 Centre for Inflammation and Metabolism, Department of Infectious Diseases and CMRC, Rigshospitalet, University of Copenhagen, DK2100, Denmark

3 The Wenner-Gren Institute, Arrhenius Laboratories, Stockholm University, SE-106 91 Stockholm, Sweden

4 Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK

5 Department of Biochemistry, Scripps Research Institute, Jupiter, FL33458, USA

6 Royal Veterinary College, University of London, Royal College Street, London, NW1, UK

7 Centre for Healthy Ageing, Department of Biomedical Sciences, Panum Institutet, University of Copenhagen, Blegdamsvej 3B, DK-2200, Denmark

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Genome Medicine 2010, 2:9 doi:10.1186/gm130

Published: 1 February 2010

Additional files

Additional file 1:

Figures S1 to S6, Tables S1 to S4 and supplementary Results and Discussion.

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Additional file 2:

miRNA lists and subject demographics.

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