Table 2

Relative risks to relatives of affected individuals calculated within the stochastic simulation for Probit, CRisch and Odds models

Probit

CRisch

Odds

K

λ_MZ

λ_Sib

λ_MZ

λ_Sib

λ_MZ

λ_Sib

0.1

0.1

1.3

1.2

0.99

1.4

1.2

1.00

1.3

1.1

1.00

0.1

0.5

3.2

1.9

0.87

5.6

2.6

0.84

3.9

2.1

0.85

0.1

0.7

4.7

2.4

0.81

7.6

3.0

0.83

6.0

2.8

0.80

0.1

0.95

7.8

3.1

0.82

9.7

3.2

0.92

9.3

3.2

0.90

0.01

0.1

1.9

1.4

0.97

2.4

1.5

1.00

1.7

1.3

1.03

0.01

0.5

13.0

4.4

0.68

51.7

9.9

0.53

34.8

8.1

0.54

0.01

0.7

26.6

7.0

0.54

76.8

12.3

0.51

62.3

11.3

0.49

0.01

0.95

67.3

11.7

0.49

97.0

13.0

0.57

94.6

12.9

0.57

0.001

0.1

2.8

1.7

0.96

4.0

2.0

1.00

1.2

1.1

1.06

0.001

0.5

54.8

10.5

0.49

516.5

41.6

0.30

342.5

34.0

0.30

0.001

0.7

157.8

20.6

0.37

796.8

51.4

0.30

638.5

49.5

0.26

0.001

0.95

599.8

47.5

0.27

989.9

57.6

0.30

968.6

55.9

0.31

is an input parameter for the Probit model. For each τ is estimated from the Probit model simulation and used as input to the CRisch and Odds model simulations. is used as the benchmark as τ is dependent on n, p and K.

Wray and Goddard Genome Medicine 2010 2:10   doi:10.1186/gm131