Genome Medicine


Open Access Highly Access Research

Networking of differentially expressed genes in human cancer cells resistant to methotrexate

Elisabet Selga, Carlota Oleaga, Sara Ramírez, M Cristina de Almagro, Véronique Noé and Carlos J Ciudad*

Author Affiliations

Department of Biochemistry and Molecular Biology, School of Pharmacy, University of Barcelona, Diagonal Avenue, E-08028 Barcelona, Spain


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Genome Medicine 2009, 1:83 doi:10.1186/gm83

Published: 4 September 2009

Additional files

Additional data file 1:

The list was generated using GeneSpring software v 7.3.1. It includes the GenBank numbers of all genes, their respective common names and the associated description. The fold change values relative to the control (sensitive cells) are provided. The differentially expressed transcripts corresponding to open reading frames, transcribed sequences, cDNA clones or hypothetical genes have been omitted. Out of the 54,675 transcripts contained in the microarray, 21,216 passed the control strength filter, 3,046 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 518 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 97KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 2:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 21,304 passed the control strength filter, 5,399 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 848 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 157KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 3:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 21,438 passed the control strength filter, 3,052 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 1,002 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 174KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 4:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 27,498 passed the control strength filter, 12 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and all of them remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 11KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 5:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 21,340 passed the control strength filter, 7,612 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 2,248 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 364KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 6:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 24,964 passed the control strength filter, 5,805 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 490 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 100KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 7:

The list was generated using GeneSpring software v 7.3.1. Out of the 54,675 transcripts contained in the microarray, 20,520 passed the control strength filter, 7,592 the Benjamini and Hochberg false discovery rate-corrected P < 0.05 filter, and 2,383 remained after filtering for at least a twofold expression difference (the genes presented in this file).

Format: XLS Size: 397KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data