Table 1

Application of antibody microarrays in cancer research

Cancer type

Sample source

Assay platform

Number of antibodies

References

Angiogenesis

Cell line

ProteoChip

60

[47]

Bladder

Human sera

Nitrocellulose FAST slides

254

[53]

Breast

Cell line, human sera and tissue

Hypromatrix, RayBio, Proteome Profiler, MaxiSorp slide, nitrocellulose membrane, Panorama cell signaling, BD antibody microarray 380

400, 174, 42, 129, 312, 224, 378

[29,49-54,61,62,70-73]

Colon

Cell line

Poly-L-lysine or superaldehyde coated glass slides

146

[63]

Colorectal

Human tissue, cell line

Lab Vision, Panorama cell signaling

720, 224

[30,64,74]

Gastric

Human sera

Lab Vision

720

[30]

Intestinal

Mouse sera

Nitrocellulose-coated slides

40

[75]

Leukemia

Human sera

DotScan

82

[76]

Liver

Human tissue, cell line

Hypromatrix

400

[48]

Lung

Human sera and exhaled breath condensate, cell line

Cytokine antibody array VI+VII, Panorama cell signaling, Nitrocellulose-coated slides

120, 224, 84

[46,55,77,78]

Melanoma

Cell line

RayBio

174

[79]

Ovarian

Human sera

Hydrogel-coated glass slides

320

[57,60]

Pancreatic

Human sera

Nitrocellulose-coated slides, MaxiSorp slide

129, 48, 90

[44,56,59,68,69]

Prostate

Cell line, human sera and prostate fluid

Phosphorylation antibody array, RayBio, hydrogels or poly-L-lysine coated slides

71, 174, 184, 86

[65-67,77,80]

Renal

Human sera

RayBio

20

[58]

Alhamdani et al. Genome Medicine 2009 1:68   doi:10.1186/gm68