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Musings
Musings on genome medicine: cholesterol and coronary artery disease
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* Corresponding author: David G Nathan david_nathan@dfci.harvard.edu
Dana-Farber Cancer Institute, Binney Street, Boston, MA 02115, USA
Genome Medicine 2009, 1:60 doi:10.1186/gm60
Published: 8 June 2009Abstract
Cholesterol levels and not inflammatory markers are the major variables that pose a risk of coronary artery disease. Diabetes greatly increases the risk at any cholesterol level. Coronary artery disease and cancer are linked by a common protein - an apoptotic protein that also functions as a regulator of insulin secretion.