Genome Medicine


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Application of serum proteomics to the Women's Health Initiative conjugated equine estrogens trial reveals a multitude of effects relevant to clinical findings

Hiroyuki Katayama, Sophie Paczesny, Ross Prentice, Aaron Aragaki, Vitor M Faca, Sharon J Pitteri, Qing Zhang, Hong Wang, Melissa Silva, Jacob Kennedy, Jacques Rossouw, Rebecca Jackson, Judith Hsia, Rowan Chlebowski, JoAnn Manson and Samir Hanash*

Genome Medicine 2009, 1:47 doi:10.1186/gm47

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Using a global proteomic approach to identify proteins affected by estrogen therapy

Timothy D Veenstra Genome Medicine 2009, 1:58 (5 June 2009)

Although global proteomic analyses involve a number of methodological challenges, they can substantially add to data gathered via other study designs by unveiling novel functional pathways and hypotheses that can help guide and prioritize further research.