Genome Medicine


Genome-based prediction of common diseases: methodological considerations for future research

A Cecile JW Janssens* and Cornelia M van Duijn

Genome Medicine 2009, 1:20 doi:10.1186/gm20

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Predictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability

Raluca Mihaescu, Ramal Moonesinghe, Muin J Khoury, A Janssens Genome Medicine 2011, 3:51 (28 July 2011)

Analysis of the predictive ability of risk models to identify high-risk groups for complex diseases highlights the importance of the frequency of the risk group and the frequency of the disease.

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Assessing the impact of a combined analysis of four common low-risk genetic variants on autism risk

Jerome Carayol, Gerard D Schellenberg, Frederic Tores, Jörg Hager, Andreas Ziegler, Geraldine Dawson Molecular Autism 2010, 1:4 (22 February 2010)

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Genome-wide association studies in pharmacogenomics: untapped potential for translation

Idris Guessous, Marta Gwinn, Muin J Khoury Genome Med 2009, 1:46 (28 April 2009)

The integration of genome-wide association studies within the design of pharmacogenomics trials is currently underexploited but holds promise for accelerating the transfer of gene discoveries into clinical practice.