Figure 5.

Overview of the key metabolic changes induced by PPARδ stimulation. (a) Metabolic pathways altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (b) Linoleate pathway altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (c) Linolenate pathway altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (d) Metabolic pathways altered in PPARδ agonist treated mice skeletal muscle. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue.