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Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor δ from Peroxisome proliferator-activated receptor γ in the ob/ob mouse

Lee D Roberts, David G Hassall, Deborah A Winegar, John N Haselden, Andrew W Nicholls and Julian L Griffin*

Genome Medicine 2009, 1:115 doi:10.1186/gm115

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Applications of metabolomics for understanding the action of peroxisome proliferator-activated receptors (PPARs) in diabetes, obesity and cancer

Zsuzsanna Ament, Mojgan Masoodi, Julian L Griffin Genome Medicine 2012, 4:32 (30 April 2012)

This article is part of a collection on Metabolomics of disease

Abstract | Full text | PDF | PubMed |  Editor’s summary

Julian Griffin and colleagues review the role metabolomics has played in elucidating the roles of peroxisome proliferator-activated receptors in systemic metabolism regulation.

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The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

Lee D Roberts, Andrew J Murray, David Menassa, Tom Ashmore, Andrew W Nicholls, Julian L Griffin Genome Biology 2011, 12:R75 (11 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A specific agonist demonstrates the contrast between PPAR-delta and PPAR-gamma function in lipid metabolism

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