Table 1

Examples of recent secretome data for major pathogens

Pathogen

Principal host

Disease

Approach used

Reference


Bacteria

Listeria monocytogenes

Human

Listeriosis

Proteomics and bioinformatics

Trost et al. [39]

Mycobacterium immunogenum

Human

Hypersensitivity pneumonitis

Proteomics and bioinformatics

Gupta et al. [30]

Helicobacter pylori

Human

Chronic gastric infection

Proteomics and bioinformatics

Löwer et al. [18]

Legionella pneumophila

Human

Legionellosis

Proteomics

Galka et al. [40]

Helminths

Ancylostoma caninum

Dog

Hookworm disease

Proteomics and bioinformatics

Mulvenna et al. [41]

Brugia malayi

Human

Lymphatic filariasis

Proteomics and bioinformatics

Hewitson et al. [42];

Moreno et al. [43]

Ostertagia ostertagi

Cattle

Ostertagiasis

Proteomics and bioinformatics

Saverwyns et al. [44]

Schistosoma mansoni

Human

Schistosomiasis

Proteomics and bioinformatics

Knudsen et al. [45];

Cass et al. [19]

Teladorsagia circumcinta

Sheep, goat

Ostertagiasis

Proteomics

Craig et al. [46]

Trichinella spiralis

Mammals

Trichinellosis

Proteomics and bioinformatics

Robinson et al. [47]

Fasciola hepatica

Cattle, sheep

Fasciolosis

Proteomics and bioinformatics

Gourbal et al. [48], Robinson et al. [15]

Meloidogyne incognita

Plant

Root-knot disease

Proteomics and bioinformatics

Bellafiore et al. [49]

Protozoa

Plasmodium falciparum

Human

Malaria

Proteomics and bioinformatics

van Ooij et al. [17]

Leishmania donovani

Human, rat, canids, hyraxes

Leishmaniasis

Proteomics and bioinformatics

Silverman et al. [11]

Fungi

Penicillium citrinum

Human

Allergic reactions

Proteomics

Chiu et al. [50]

Magnaporthe grisea

Plant

Blast disease

Proteomics

Kim et al. [51]

Viruses

Dengue virus

Human

Dengue hemorrhagic fever

Proteomics and bioinformatics

Higa et al. [12]


Ranganathan and Garg Genome Medicine 2009 1:113   doi:10.1186/gm113