Genome Medicine




Medicine in the post-genomic era

Genome Medicine publishes peer-reviewed research articles, new methods and software tools in all areas of medicine studied from a post-genomic perspective. The journal also provides review and comment on the latest advances in translational genomics and personalized medicine, and their implications for the clinical and ethical management of human health and disease.

Editor

  • Rebecca Furlong, PhD

Articles

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  • Genetic overlap in autoimmune disorders

    Lindsey Criswell and Corinne Richard-Miceli review risk loci that are shared among autoimmune disorders and how this information might help to explain common disease mechanisms.

    Genome Medicine 2012, 4:6
  • Image attributed to: Image of human ES cells_wikimedia

    An update on stem cell therapeutics

    Sarah Crawford presents the highlights and roadblocks of therapeutic applications from the Euroepistem 2011 meeting on 'Epigenomic Programming and Stem Cells for Drug Discovery'.

    Genome Medicine 2012, 4:5
  • Side-effects as clinical markers

    Miquel Duran-Frigola and Patrick Aloy discuss a new computational approach to systematically exploring novel potential applications of already marketed drugs in distinct therapeutic areas.

    Genome Medicine 2012, 4:3
  • Image attributed to: Authors figure 1 showing splice variants

    PTPN22 expression in rheumatoid arthritis

    Genotyping and phenotyping of cells from rheumatoid arthritis patients and healthy controls reveals different patterns of expression for the protein tyrosine phosphatase non-receptor 22 gene.

    Genome Medicine 2012, 4:2
  • Image attributed to: Brain imaging fig adapted from authors fig3

    Lipid biomarkers in schizophrenia

    Lipidomic, imaging and neurocognitive analysis of twin pairs reveals lipid biomarkers linked to decreased cognitive speed and potentially increased susceptibility to infection in schizophrenia.

    Genome Medicine 2012, 4:1
  • Predicting responses to sunitinib

    Ganapathi and Bukowski discuss the advances and pitfalls of a recent study of single nucleotide polymorphisms to predict the activity or toxicity of sunitinib for clear cell renal cell carcinoma.

    Genome Medicine 2011, 3:79
  • Image attributed to: Image of zebrafish, modified from article

    Hematopoiesis and disease - the zebrafish model

    Martin, Moriyama and Zon review the advantages of zebrafish for studying early development of blood cells and highlight recent discoveries using this model that show clinical promise.

    Genome Medicine 2011, 3:83
  • Genetic test advertising in the United States

    Melanie Myers reviews the impact of advertising and selling of genetic testing direct to consumers on health care providers and asks whether providers are ready to deal with this issue.

    Genome Medicine 2011, 3:81

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International data sharing in medicine
Doctors act on genotype information
Predicting cis-regulatory mutations
Translational stem cell genomics image

Risk_Models
Monthly issues alert

Latest issue

Genome Medicine Volume 3 Issue 12

The complete issue of Genome Medicine Volume 3 Issue 12 is now available.

Featured free review

ES-cell-specific signatures in cancer


figure

Jonghwan Kim and Stuart Orkin review recent genome-scale and systems approaches to understand the regulatory networks that are common to embryonic stem (ES) cells and cancer.


View more review articles

Quotes

Muin Khoury
The long term success of genomic medicine depends on establishing a strong evidence base for its validity and utility using clinical and population translational studies. Genome Medicine can be a forum for publishing original research and systematic reviews beyond bench to bedside.

Dr Muin Khoury,
Section Editor, Genome Medicine
Office of Public Health Genomics, CDC
Epidemiology and Genetics Research Program, NCI

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