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Medicine in the post-genomic era
Current Issue
The complete issue of Genome Medicine Volume 1 Issue 6 is now available in full online
Table of contents
Aims & scope
Genome Medicine is an online peer-reviewed journal which publishes open access research articles of outstanding quality in all areas of medicine studied from a genomic or post-genomic perspective. The journal has a special focus on the latest technologies and findings that have an impact on the understanding and management of human health and disease.
Musings on genome medicine
Each issue of Genome Medicine features a regular column by David G Nathan and Stuart Orkin tackling a variety of controversial topics and providing a unique, exciting perspective on the events and developments in genomic medicine.
Latest review
All reviews, commentaries and reports published in Genome Medicine are free to read. See below for the latest free review.
Quotes
“High-throughput experimental and computational technologies are revolutionizing our understanding of life by enabling global systems approaches beyond classical analytical molecular and cellular biology.
Genome Medicine is a timely initiative to foster this transition from the highly fragmented scientific and medical landscape to the integrative systems biology and medicine which are needed to translate fundamental discoveries into useful healthcare services for the benefit of individual patients worldwide.
Professor Charles Auffray,
Genome Medicine Section Editor
LGN CNRS/Université Pierre et Marie Curie, France.
Featured articles
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Genome Medicine
2009,
1:65
The combination of pathway-based approaches and genome-wide association studies can help to detect important single-locus effects, as shown by a recent study on multiple sclerosis.
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Genome Medicine
2009,
1:64
Investigators empowered by bioinformatics need to take on the role of translational scientist by building the tools to ask the questions that will yield discoveries which will improve human health.
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Genome Medicine
2009,
1:63
Genomic and post-genomic analyses have led to new insights in our understanding of human prion diseases and give new hope for patient therapy.
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Genome Medicine
2009,
1:62
Germline and somatic copy number variations play an increasingly important role in both the predisposition to and the pathogenesis of cancer.
Latest articles 
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Genome Medicine
2009,
1:65
(29 June 2009)
The combination of pathway-based approaches and genome-wide association studies can help to detect important single-locus effects, as shown by a recent study on multiple sclerosis.
-
Genome Medicine
2009,
1:64
(29 June 2009)
Investigators empowered by bioinformatics need to take on the role of translational scientist by building the tools to ask the questions that will yield discoveries which will improve human health.
-
Genome Medicine
2009,
1:63
(22 June 2009)
Genomic and post-genomic analyses have led to new insights in our understanding of human prion diseases and give new hope for patient therapy.
-
Genome Medicine
2009,
1:62
(16 June 2009)
Germline and somatic copy number variations play an increasingly important role in both the predisposition to and the pathogenesis of cancer.
-
Genome Medicine
2009,
1:61
(12 June 2009)
A report on the Biology of Genomes meeting held at Cold Spring Harbor Laboratory, NY, USA, 5-9 May 2009
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Genome Medicine
2009,
1:59
(8 June 2009)
With increasing evidence showing that microRNA-96 is crucial to the development and maintenance of inner ear hair cells and hearing, interest in microRNAs as therapeutic agents or target molecules to preserve or restore hearing is growing.
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Genome Medicine
2009,
1:60
(8 June 2009)
We should not be distracted by inflammation, which is a secondary consequence of atherosclerosis and therefore less important than cholesterol in the pathogenesis of coronary artery disease.
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Genome Medicine
2009,
1:58
(5 June 2009)
Although global proteomic analyses involve a number of methodological challenges, they can substantially add to data gathered via other study designs by unveiling novel functional pathways and hypotheses that can help guide and prioritize further research.
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Genome Medicine
2009,
1:57
(4 June 2009)
New technologies are enabling the identification of glycosylation sites and glycans in proteins from complex proteomic mixtures, which will help to identify cancer biomarkers.
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Genome Medicine
2009,
1:55
(29 May 2009)
The strong association between germline polymorphisms and myeloproliferative neoplasms in patients positive for a mutation in the JAK2 gene may provide new possibilities for the pathogenesis of these cancers.
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Genome Medicine
2009,
1:56
(29 May 2009)
Novel technologies that permit simultaneous genomic, epigenomic and expression analyses will improve our understanding of the biological and pathological processes mediated by allele-specific expression. leading to a better understanding of disease.
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Genome Medicine
2009,
1:54
(22 May 2009)
Through genomic approaches and technologies, a region on 4q25 has been identified as a common susceptibility factor for atrial fibrillation and the PITX2 gene has been identified as the causal variant; more such variants will soon be identified.
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Genome Medicine
2009,
1:53
(21 May 2009)
A report on the Proteomic Forum 2009 conference, Berlin, Germany, 29 March to 2 April, 2009.
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Genome Medicine
2009,
1:52
(18 May 2009)
A report on the Genetics and Genomics of Infectious Diseases conference, Singapore, 21-24 March 2009.
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Genome Medicine
2009,
1:51
(12 May 2009)
The protective allele for diabetes and the risk allele for coronary heart disease at the 9p21.3 locus have varying haplotype frequencies across 51 populations, implying very different population histories and highlighting the need to consider allelic background data for replication studies of genetic associations.
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