Medicine in the post-genomic era
Genome Medicine publishes peer-reviewed research articles, new methods and software tools in all areas of medicine studied from a post-genomic perspective. The journal also provides review and comment on the latest advances in translational genomics and personalized medicine, and their implications for the clinical and ethical management of human health and disease.
- Rebecca Furlong, PhD
David Gurwitz argues that expression profiling is currently the most promising and cost-effective tool for discovery of new prognostic, diagnostic and therapeutic biomarkers.
Kuzmanov and Emili review recent advances in protein-protein interaction studies from various model organisms, shedding light on the mechanisms and possible treatments for human disease.
Key genes in cultured rheumatoid arthritis cells are stably differentially methylated compared to osteoarthritis or normal cells, and are potential therapeutic targets.
Caitlin Farris and Jeffrey Trimarchi discuss how a new non-invasive approach for personalized diagnosis of prostate cancer shows promise for the clinic, being both time- and cost-effective.
Louis Muglia and colleagues review the genetics and genomics of pre-term birth and birth timing, discussing the limitations of animal models and the progress of human studies.
Mark Pallen and co-authors review advances in applying high-throughput sequencing approaches for outbreak investigation (focusing on bacterial infections), and discuss the implications for clinical microbiology.
Knoppers, Thorogood and Chadwick muse over the evolution of ethical statements and policy over the course of the human genome project and beyond, marking 10 years since its completion.
A fully automated high-throughput method provides proof-of-concept that fatty acid profiling of human plasma is achievable for metabolic phenotyping in large epidemiological and genetic studies.
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- Just pub'd: Gurwitz argues that expression profiling is currently the best tool for discovery of new biomarkers. http://t.co/x3Uq8U1g8m 2:30 PM May 14th, 2013
- RT @CCTrials: ISRCTN survey & chance to win £100 Amazon vouchers: Help us improve our services by completing this short survey http://t.co/… 8:41 AM May 14th, 2013
- RT @DrKhouryCDC: CDC Genomics & Health Impact Update, May 2: Malaria, Vaccines, Prematurity, Arthritis, Hypertension & More http://… 2:04 PM May 7th, 2013
Microbes in human health and disease
Edited by: Dr Martin L. Hibberd
Published: 29 April 2013
Musings on Genome Medicine
Published: 29 April 2013
Last updated: 14 May 2013
Proteomic applications in medicine
Edited by: Sabine Bahn, Dr Paul Guest
Published: 27 February 2013
Last updated: 30 April 2013